Cargando…
Wnt-Signaling Inhibitor Wnt-C59 Suppresses the Cytokine Upregulation in Multiple Organs of Lipopolysaccharide-Induced Endotoxemic Mice via Reducing the Interaction between β-Catenin and NF-κB
Sepsis is characterized by multiple-organ dysfunction caused by the dysregulated host response to infection. Until now, however, the role of the Wnt signaling has not been fully characterized in multiple organs during sepsis. This study assessed the suppressive effect of a Wnt signaling inhibitor, W...
Autores principales: | Jang, Jaewoong, Song, Jaewon, Sim, Inae, Kwon, Young V., Yoon, Yoosik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230366/ https://www.ncbi.nlm.nih.gov/pubmed/34200709 http://dx.doi.org/10.3390/ijms22126249 |
Ejemplares similares
-
Wnt-C59 inhibits proinflammatory cytokine expression by reducing the interaction between β-catenin and NF-κB in LPS-stimulated epithelial and macrophage cells
por: Jang, Jaewoong, et al.
Publicado: (2021) -
LGK974 suppresses lipopolysaccharide-induced endotoxemia in mice by modulating the crosstalk between the Wnt/β-catenin and NF-κB pathways
por: Jang, Jaewoong, et al.
Publicado: (2021) -
LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974
por: Jang, Jaewoong, et al.
Publicado: (2017) -
Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation
por: Ma, Bin, et al.
Publicado: (2016) -
Wnt1 Participates in Inflammation Induced by Lipopolysaccharide Through Upregulating Scavenger Receptor A and NF-kB
por: Zhao, Wenting, et al.
Publicado: (2015)