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Plasticity in Neuroblastoma Cell Identity Defines a Noradrenergic-to-Mesenchymal Transition (NMT)

SIMPLE SUMMARY: Neuroblastoma arises in the developing sympathetic nervous system and represents the most common extracranial pediatric solid tumor. High-risk patients often experience relapse despite intensive multimodal therapies. Consistent with previous reports describing various phenotypes in n...

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Detalles Bibliográficos
Autores principales: Gautier, Margot, Thirant, Cécile, Delattre, Olivier, Janoueix-Lerosey, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230375/
https://www.ncbi.nlm.nih.gov/pubmed/34200747
http://dx.doi.org/10.3390/cancers13122904