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A Reliable and Standardizable Differential PCR and qPCR Methodology Assesses HER2 Gene Amplification in Gastric Cancer

SIMPLE SUMMARY: Patients with gastric cancer may present variations in the copy number of the HER2 gene in their primary tumors. The techniques used to detect these variations and HER2 overexpression render false positive and negative results with high frequency, and robust methodologies are require...

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Detalles Bibliográficos
Autores principales: Juarez, Ignacio, Toro-Fernandez, Juan Francisco, Vaquero-Yuste, Christian, Molina-Alejandre, Marta, Lasa, Inmaculada, Gomez, Remedios, Lopez, Adela, Martin-Villa, Jose Manuel, Gutierrez, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230392/
https://www.ncbi.nlm.nih.gov/pubmed/34200787
http://dx.doi.org/10.3390/biology10060516