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Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes

Articular cartilage is a connective tissue lining the surfaces of synovial joints. When the cartilage severely wears down, it leads to osteoarthritis (OA), a debilitating disease that affects millions of people globally. The articular cartilage is composed of a dense extracellular matrix (ECM) with...

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Detalles Bibliográficos
Autores principales: Sebastian, Aimy, McCool, Jillian L., Hum, Nicholas R., Murugesh, Deepa K., Wilson, Stephen P., Christiansen, Blaine A., Loots, Gabriela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230441/
https://www.ncbi.nlm.nih.gov/pubmed/34200880
http://dx.doi.org/10.3390/cells10061462