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Evaluation of the effects of the T-type calcium channel enhancer SAK3 in a rat model of TAF1 deficiency
The TATA-box binding protein associated factor 1 (TAF1) is part of the TFIID complex that plays a key role during the initiation of transcription. Variants of TAF1 are associated with neurodevelopmental disorders. Previously, we found that CRISPR/Cas9 based editing of the TAF1 gene disrupts the morp...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230513/ https://www.ncbi.nlm.nih.gov/pubmed/33359140 http://dx.doi.org/10.1016/j.nbd.2020.105224 |