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Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation

Oxidative stress is crucial to the outbreak and advancement of neurodegenerative diseases and is a common factor to many of them. We describe the synthesis of a library of derivatives of the 4-arylmethylen-2-pyrrolin-5-one framework by sequential application of a three-component reaction of primary...

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Detalles Bibliográficos
Autores principales: Cores, Ángel, Abril, Sheila, Michalska, Patrycja, Duarte, Pablo, Olives, Ana I., Martín, M. Antonia, Villacampa, Mercedes, León, Rafael, Menéndez, J. Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230565/
https://www.ncbi.nlm.nih.gov/pubmed/34200859
http://dx.doi.org/10.3390/antiox10060941