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Bisavenathramide Analogues as Nrf2 Inductors and Neuroprotectors in In Vitro Models of Oxidative Stress and Hyperphosphorylation
Oxidative stress is crucial to the outbreak and advancement of neurodegenerative diseases and is a common factor to many of them. We describe the synthesis of a library of derivatives of the 4-arylmethylen-2-pyrrolin-5-one framework by sequential application of a three-component reaction of primary...
Autores principales: | Cores, Ángel, Abril, Sheila, Michalska, Patrycja, Duarte, Pablo, Olives, Ana I., Martín, M. Antonia, Villacampa, Mercedes, León, Rafael, Menéndez, J. Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230565/ https://www.ncbi.nlm.nih.gov/pubmed/34200859 http://dx.doi.org/10.3390/antiox10060941 |
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