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Rad52 Oligomeric N-Terminal Domain Stabilizes Rad51 Nucleoprotein Filaments and Contributes to Their Protection against Srs2

Homologous recombination (HR) depends on the formation of a nucleoprotein filament of the recombinase Rad51 to scan the genome and invade the homologous sequence used as a template for DNA repair synthesis. Therefore, HR is highly accurate and crucial for genome stability. Rad51 filament formation i...

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Detalles Bibliográficos
Autores principales: Ma, Emilie, Maloisel, Laurent, Le Falher, Léa, Guérois, Raphaël, Coïc, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230603/
https://www.ncbi.nlm.nih.gov/pubmed/34207997
http://dx.doi.org/10.3390/cells10061467