Etoposide Triggers Cellular Senescence by Inducing Multiple Centrosomes and Primary Cilia in Adrenocortical Tumor Cells

Etoposide (ETO) has been used in treating adrenocortical tumor (ACT) cells. Our previous study showed that ETO inhibits ACT cell growth. In the present study, we show that ETO treatment at IC50 (10 μM) inhibited ACT cell growth by inducing cellular senescence rather than apoptosis. Several markers o...

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Detalles Bibliográficos
Autores principales: Teng, Yen-Ni, Chang, Huei-Cih, Chao, Yu-Ying, Cheng, Hui-Ling, Lien, Wei-Chih, Wang, Chia-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230646/
https://www.ncbi.nlm.nih.gov/pubmed/34208028
http://dx.doi.org/10.3390/cells10061466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230646/
https://www.ncbi.nlm.nih.gov/pubmed/34208028
http://dx.doi.org/10.3390/cells10061466

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