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Barriers to Small Molecule Drug Discovery for Systemic Amyloidosis
Inhibition of amyloid fibril formation could benefit patients with systemic amyloidosis. In this group of diseases, deposition of amyloid fibrils derived from normally soluble proteins leads to progressive tissue damage and organ failure. Amyloid formation is a complex process, where several individ...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230685/ https://www.ncbi.nlm.nih.gov/pubmed/34208058 http://dx.doi.org/10.3390/molecules26123571 |