MPLA and AddaVax(®) Adjuvants Fail to Promote Intramuscular LaAg Vaccine Protectiveness against Experimental Cutaneous Leishmaniasis

There is so far no vaccine approved for human leishmaniasis, mainly because of the lack of appropriate adjuvants. This study aimed to evaluate in mice the capacity of a mixture of monophosphoryl lipid A (MPLA) and AddaVax(®) adjuvants in enhancing the efficacy of a Leishvacin(®)-like vaccine compris...

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Detalles Bibliográficos
Autores principales: Oliveira-Maciel, Diogo, dos-Santos, Júlio Souza, Oliveira-Silva, Gabriel, de Mello, Mirian França, da Fonseca-Martins, Alessandra Marcia, Carneiro, Monique Pacheco Duarte, Ramos, Tadeu Diniz, Firmino-Cruz, Luan, Gomes, Daniel Claudio Oliveira, Rossi-Bergmann, Bartira, de Matos Guedes, Herbert Leonel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230739/
https://www.ncbi.nlm.nih.gov/pubmed/34207948
http://dx.doi.org/10.3390/microorganisms9061272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230739/
https://www.ncbi.nlm.nih.gov/pubmed/34207948
http://dx.doi.org/10.3390/microorganisms9061272

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