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LPS Primes Brain Responsiveness to High Mobility Group Box-1 Protein

High mobility group box (HMGB)1 action contributes to late phases of sepsis, but the effects of increased endogenous plasma HMGB1 levels on brain cells during inflammation are unclear. Here, we aimed to further investigate the role of HMGB1 in the brain during septic-like lipopolysaccharide-induced...

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Detalles Bibliográficos
Autores principales: Peek, Verena, Harden, Lois M., Damm, Jelena, Aslani, Ferial, Leisengang, Stephan, Roth, Joachim, Gerstberger, Rüdiger, Meurer, Marita, von Köckritz-Blickwede, Maren, Schulz, Sabine, Spengler, Bernhard, Rummel, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230749/
https://www.ncbi.nlm.nih.gov/pubmed/34208101
http://dx.doi.org/10.3390/ph14060558