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Integrated Multi-Class Classification and Prediction of GPCR Allosteric Modulators by Machine Learning Intelligence

G-protein-coupled receptors (GPCRs) are the largest and most diverse group of cell surface receptors that respond to various extracellular signals. The allosteric modulation of GPCRs has emerged in recent years as a promising approach for developing target-selective therapies. Moreover, the discover...

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Detalles Bibliográficos
Autores principales: Hou, Tianling, Bian, Yuemin, McGuire, Terence, Xie, Xiang-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230833/
https://www.ncbi.nlm.nih.gov/pubmed/34208096
http://dx.doi.org/10.3390/biom11060870