Subcutaneously Injectable Hyaluronic Acid Hydrogel for Sustained Release of Donepezil with Reduced Initial Burst Release: Effect of Hybridization of Microstructured Lipid Carriers and Albumin

The daily oral administration of acetylcholinesterase (AChE) inhibitors for Alzheimer’s disease features low patient compliance and can lead to low efficacy or high toxicity owing to irregular intake. Herein, we developed a subcutaneously injectable hyaluronic acid hydrogel (MLC/HSA hydrogel) hybrid...

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Detalles Bibliográficos
Autores principales: Kang, Nae-Won, Yoon, So-Yeon, Kim, Sungho, Yu, Na-Young, Park, Ju-Hwan, Lee, Jae-Young, Cho, Hyun-Jong, Kim, Dae-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230846/
https://www.ncbi.nlm.nih.gov/pubmed/34208289
http://dx.doi.org/10.3390/pharmaceutics13060864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230846/
https://www.ncbi.nlm.nih.gov/pubmed/34208289
http://dx.doi.org/10.3390/pharmaceutics13060864

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