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HK2 Mediated Glycolytic Metabolism in Mouse Photoreceptors Is Not Required to Cause Late Stage Age-Related Macular Degeneration-Like Pathologies

Age-related macular degeneration (AMD) is a multifactorial disease of unclear etiology. We previously proposed that metabolic adaptations in photoreceptors (PRs) play a role in disease progression. We mimicked these metabolic adaptations in mouse PRs through deletion of the tuberous sclerosis comple...

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Detalles Bibliográficos
Autores principales: Cheng, Shun-Yun, Malachi, Anneliese, Cipi, Joris, Ma, Shan, Brush, Richard S., Agbaga, Martin-Paul, Punzo, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230848/
https://www.ncbi.nlm.nih.gov/pubmed/34208233
http://dx.doi.org/10.3390/biom11060871