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Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: study protocol for the randomised controlled phase II ReSScue trial

INTRODUCTION: In the multisystem inflammatory disorder systemic sclerosis (SSc), gastrointestinal tract (GIT) affliction is highly prevalent. There are no known disease modifying therapies and the negative impact is substantial. Aiming for a new therapeutic principle, and inspired by recent work sho...

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Detalles Bibliográficos
Autores principales: Hoffmann-Vold, Anna-Maria, Fretheim, Håvard H, Sarna, Vikas K, Barua, Imon, Carstens, Maylen N, Distler, Oliver, Khanna, Dinesh, Volkmann, Elizabeth R, Midtvedt, Øyvind, Didriksen, Henriette, Dhainaut, Alvilde, Halse, Anne-Kristine, Bakland, Gunnstein, Pesonen, Maiju, Olsen, Inge, Molberg, Øyvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231046/
https://www.ncbi.nlm.nih.gov/pubmed/34168032
http://dx.doi.org/10.1136/bmjopen-2020-048541