Cargando…

Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: study protocol for the randomised controlled phase II ReSScue trial

INTRODUCTION: In the multisystem inflammatory disorder systemic sclerosis (SSc), gastrointestinal tract (GIT) affliction is highly prevalent. There are no known disease modifying therapies and the negative impact is substantial. Aiming for a new therapeutic principle, and inspired by recent work sho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hoffmann-Vold, Anna-Maria, Fretheim, Håvard H, Sarna, Vikas K, Barua, Imon, Carstens, Maylen N, Distler, Oliver, Khanna, Dinesh, Volkmann, Elizabeth R, Midtvedt, Øyvind, Didriksen, Henriette, Dhainaut, Alvilde, Halse, Anne-Kristine, Bakland, Gunnstein, Pesonen, Maiju, Olsen, Inge, Molberg, Øyvind
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Rheumatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231046/ https://www.ncbi.nlm.nih.gov/pubmed/34168032 http://dx.doi.org/10.1136/bmjopen-2020-048541

Ejemplares similares

Differential sensitivity of the 2020 revised comprehensive diagnostic criteria and the 2019 ACR/EULAR classification criteria across IgG4-related disease phenotypes: results from a Norwegian cohort
por: Vikse, Jens, et al.
Publicado: (2023)

Effects of faecal microbiota transplantation on the small intestinal mucosa in systemic sclerosis
por: Strahm, Noemi, et al.
Publicado: (2023)

Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
por: Fretheim, Håvard, et al.
Publicado: (2020)

Target organ expression and biomarker characterization of chemokine CCL21 in systemic sclerosis associated pulmonary arterial hypertension
por: Didriksen, Henriette, et al.
Publicado: (2022)

Serum markers of cardiac complications in a systemic sclerosis cohort
por: Tennøe, Anders H., et al.
Publicado: (2022)

Celebrating Achim Trebst’s 80th birthday
por: ter Meulen, Volker, et al.
Publicado: (2009)

Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
por: Fretheim, Håvard, et al.
Publicado: (2020)

Systolic Dysfunction in Systemic Sclerosis: Prevalence and Prognostic Implications
por: Tennøe, Anders H., et al.
Publicado: (2019)

Gastrointestinal symptom severity and progression in systemic sclerosis
por: van Leeuwen, Nina M, et al.
Publicado: (2022)

Bone mineral density in patients with psoriatic arthritis: data from the Nord-Trøndelag Health Study 3
por: Gulati, Agnete Malm, et al.
Publicado: (2017)

Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts
por: Volkmann, Elizabeth R, et al.
Publicado: (2017)

International Symposium on Nuclei and Nucleons : Festschrift Richter (Achim) on his 60th Birthday
por: Braun-Munzinger, Peter, et al.
Publicado: (2000)

TNF inhibitors appear to inhibit disease progression and improve outcome in Takayasu arteritis; an observational, population-based time trend study
por: Gudbrandsson, Birgir, et al.
Publicado: (2017)

Augmented concentrations of CX(3)CL1 are associated with interstitial lung disease in systemic sclerosis
por: Hoffmann-Vold, Anna-Maria, et al.
Publicado: (2018)

Cortical Hand Bone Porosity and Its Association with Distal Radius Fracture in Middle Aged and Elderly Women
por: Dhainaut, Alvilde, et al.
Publicado: (2013)

Long-term in-vitro precision of direct digital X-ray radiogrammetry
por: Dhainaut, Alvilde, et al.
Publicado: (2011)

Exploring the relationship between bone density and severity of distal radius fragility fracture in women
por: Dhainaut, Alvilde, et al.
Publicado: (2014)

Disease Activity and Patient-Reported Health Measures in Relation to Cytokine Levels in Ankylosing Spondylitis
por: Nossent, Johannes C., et al.
Publicado: (2019)

IL-1A gene variation in relation to cytokine levels and clinical characteristics in ankylosing spondylitis
por: Nossent, Johannes C., et al.
Publicado: (2019)

IL23R gene variants in relation to IL17A levels and clinical phenotype in patients with ankylosing spondylitis
por: Nossent, Johannes C, et al.
Publicado: (2018)

Long-Term Outcome in Systemic Lupus Erythematosus; Knowledge from Population-Based Cohorts
por: Reppe Moe, Sigrid, et al.
Publicado: (2021)

Obesity Increases Disease Activity of Norwegian Patients with Axial Spondyloarthritis: Results from the European Map of Axial Spondyloarthritis Survey
por: Bindesbøll, Christian, et al.
Publicado: (2020)

Successful treatment of spontaneous kidney graft decapsulation 18 years after renal transplantation: a case report
por: Myhre, Hans-Arne, et al.
Publicado: (2010)

Comparative analyses of muscle MRI and muscular function in anti-synthetase syndrome patients and matched controls: a cross-sectional study
por: Andersson, Helena, et al.
Publicado: (2017)

Impact of baseline clinical and radiological features on outcome of chronic rhinosinusitis in granulomatosis with polyangiitis
por: Holme, Sigrun Skaar, et al.
Publicado: (2021)

Associations between circulating endostatin levels and vascular organ damage in systemic sclerosis and mixed connective tissue disease: an observational study
por: Reiseter, Silje, et al.
Publicado: (2015)

Physical activity in patients with oligo- and polyarticular juvenile idiopathic arthritis diagnosed in the era of biologics: a controlled cross-sectional study
por: Risum, Kristine, et al.
Publicado: (2018)

Development of CT-based methods for longitudinal analyses of paranasal sinus osteitis in granulomatosis with polyangiitis
por: Holme, Sigrun Skaar, et al.
Publicado: (2019)

Norwegian society of rheumatology recommendations on diagnosis and treatment of patients with giant cell arteritis
por: Haaversen, Anne Bull, et al.
Publicado: (2023)

Effectiveness of Baby‐friendly community health services on exclusive breastfeeding and maternal satisfaction: a pragmatic trial
por: Bærug, Anne, et al.
Publicado: (2016)

Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate
por: Pollmann, Sylvie, et al.
Publicado: (2011)

Mesenchymal stem cells and T cells in the formation of Tertiary Lymphoid Structures in Lupus Nephritis
por: Dorraji, S. Esmaeil, et al.
Publicado: (2018)

Disease evolution in mixed connective tissue disease: results from a long-term nationwide prospective cohort study
por: Reiseter, Silje, et al.
Publicado: (2017)

Serious infections in patients with rheumatoid arthritis and psoriatic arthritis treated with tumour necrosis factor inhibitors: data from register linkage of the NOR-DMARD study
por: Christensen, Ingrid Egeland, et al.
Publicado: (2022)

Discontinuation rate of sulfasalazine, leflunomide and methotrexate due to adverse events in a real-life setting (NOR-DMARD)
por: Mielnik, Pawel, et al.
Publicado: (2023)

The Molecular Basis for Oat Intolerance in Patients with Celiac Disease
por: Arentz-Hansen, Helene, et al.
Publicado: (2004)

Adipokine profile in long-term juvenile dermatomyositis, and associations with adipose tissue distribution and cardiac function: a cross-sectional study
por: Marstein, Henriette Schermacher, et al.
Publicado: (2023)

Predictors of progression in systemic sclerosis patients with interstitial lung disease
por: Distler, Oliver, et al.
Publicado: (2020)

Detection of misfolded protein aggregates from a clinical perspective
por: Strømland, Øyvind, et al.
Publicado: (2016)

The Training Characteristics of World-Class Male Long-Distance Cross-Country Skiers
por: Torvik, Per-Øyvind, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9q7ib4rte0b47eqiofhqmm06dl