EPHA2-dependent outcompetition of KRASG12D mutant cells by wild-type neighbors in the adult pancreas

As we age, our tissues are repeatedly challenged by mutational insult, yet cancer occurrence is a relatively rare event. Cells carrying cancer-causing genetic mutations compete with normal neighbors for space and survival in tissues. However, the mechanisms underlying mutant-normal competition in ad...

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Detalles Bibliográficos
Autores principales: Hill, William, Zaragkoulias, Andreas, Salvador-Barbero, Beatriz, Parfitt, Geraint J., Alatsatianos, Markella, Padilha, Ana, Porazinski, Sean, Woolley, Thomas E., Morton, Jennifer P., Sansom, Owen J., Hogan, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231095/
https://www.ncbi.nlm.nih.gov/pubmed/33891893
http://dx.doi.org/10.1016/j.cub.2021.03.094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231095/
https://www.ncbi.nlm.nih.gov/pubmed/33891893
http://dx.doi.org/10.1016/j.cub.2021.03.094

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