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Zeb1 and SK3 Channel Are Up-Regulated in Castration-Resistant Prostate Cancer and Promote Neuroendocrine Differentiation

SIMPLE SUMMARY: Currently, neuroendocrine prostate cancers remain fatal, so it is crucial to better understand mechanisms of resistance to hormone therapy driving this phenotype. We have shown that Enza, a new generation hormone therapy, promotes prostate cancer cells neurodifferentiation by activat...

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Detalles Bibliográficos
Autores principales: Bery, Fanny, Cancel, Mathilde, Guéguinou, Maxime, Potier-Cartereau, Marie, Vandier, Christophe, Chantôme, Aurélie, Guibon, Roseline, Bruyère, Franck, Fromont, Gaëlle, Mahéo, Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231145/
https://www.ncbi.nlm.nih.gov/pubmed/34204608
http://dx.doi.org/10.3390/cancers13122947