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CARTmath—A Mathematical Model of CAR-T Immunotherapy in Preclinical Studies of Hematological Cancers

SIMPLE SUMMARY: CAR-T cell immunotherapy uses engineered T lymphocytes to recognize cancer antigens and to directly attack cancer cells and have been successfully used against cancers of hematopoietic origin. New CAR designs involving different and multiple target antigens and co-stimulatory structu...

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Detalles Bibliográficos
Autores principales: Barros, Luciana R. C., Paixão, Emanuelle A., Valli, Andrea M. P., Naozuka, Gustavo T., Fassoni, Artur C., Almeida, Regina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231202/
https://www.ncbi.nlm.nih.gov/pubmed/34208323
http://dx.doi.org/10.3390/cancers13122941