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CARTmath—A Mathematical Model of CAR-T Immunotherapy in Preclinical Studies of Hematological Cancers
SIMPLE SUMMARY: CAR-T cell immunotherapy uses engineered T lymphocytes to recognize cancer antigens and to directly attack cancer cells and have been successfully used against cancers of hematopoietic origin. New CAR designs involving different and multiple target antigens and co-stimulatory structu...
Autores principales: | Barros, Luciana R. C., Paixão, Emanuelle A., Valli, Andrea M. P., Naozuka, Gustavo T., Fassoni, Artur C., Almeida, Regina C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231202/ https://www.ncbi.nlm.nih.gov/pubmed/34208323 http://dx.doi.org/10.3390/cancers13122941 |
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