Amyloid Beta-Mediated Changes in Synaptic Function and Spine Number of Neocortical Neurons Depend on NMDA Receptors

Onset and progression of Alzheimer’s disease (AD) pathophysiology differs between brain regions. The neocortex, for example, is a brain region that is affected very early during AD. NMDA receptors (NMDARs) are involved in mediating amyloid beta (Aβ) toxicity. NMDAR expression, on the other hand, can...

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Detalles Bibliográficos
Autores principales: Back, Michaela K., Ruggieri, Sonia, Jacobi, Eric, von Engelhardt, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231237/
https://www.ncbi.nlm.nih.gov/pubmed/34208315
http://dx.doi.org/10.3390/ijms22126298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231237/
https://www.ncbi.nlm.nih.gov/pubmed/34208315
http://dx.doi.org/10.3390/ijms22126298

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