Influence of N-Methylation and Conformation on Almiramide Anti-Leishmanial Activity

The almiramide N-methylated lipopeptides exhibit promising activity against trypanosomatid parasites. A structure–activity relationship study has been performed to examine the influences of N-methylation and conformation on activity against various strains of leishmaniasis protozoan and on cytotoxic...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Anh Minh Thao, Brettell, Skye, Douanne, Noélie, Duquette, Claudia, Corbeil, Audrey, Fajardo, Emanuella F., Olivier, Martin, Fernandez-Prada, Christopher, Lubell, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231256/
https://www.ncbi.nlm.nih.gov/pubmed/34204673
http://dx.doi.org/10.3390/molecules26123606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231256/
https://www.ncbi.nlm.nih.gov/pubmed/34204673
http://dx.doi.org/10.3390/molecules26123606

Ejemplares similares