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Influence of N-Methylation and Conformation on Almiramide Anti-Leishmanial Activity

The almiramide N-methylated lipopeptides exhibit promising activity against trypanosomatid parasites. A structure–activity relationship study has been performed to examine the influences of N-methylation and conformation on activity against various strains of leishmaniasis protozoan and on cytotoxic...

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Detalles Bibliográficos
Autores principales:	Nguyen, Anh Minh Thao, Brettell, Skye, Douanne, Noélie, Duquette, Claudia, Corbeil, Audrey, Fajardo, Emanuella F., Olivier, Martin, Fernandez-Prada, Christopher, Lubell, William D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231256/ https://www.ncbi.nlm.nih.gov/pubmed/34204673 http://dx.doi.org/10.3390/molecules26123606

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