Methylation of CYP1A1 and VKORC1 promoter associated with stable dosage of warfarin in Chinese patients

OBJECTIVE: To investigate the association between DNA methylation and the stable warfarin dose through genome-wide DNA methylation analysis and pyrosequencing assay. METHOD: This study included 161 patients and genome-wide DNA methylation analysis was used to screen potential warfarin dose-associate...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Shiwei, Wu, Yuan, Yan, Shuidi, Liu, Jumei, Zhao, Li, Xie, Huabin, Ge, Shengxiang, Ye, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231338/
https://www.ncbi.nlm.nih.gov/pubmed/34221714
http://dx.doi.org/10.7717/peerj.11549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231338/
https://www.ncbi.nlm.nih.gov/pubmed/34221714
http://dx.doi.org/10.7717/peerj.11549

Ejemplares similares