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Methylation of CYP1A1 and VKORC1 promoter associated with stable dosage of warfarin in Chinese patients

OBJECTIVE: To investigate the association between DNA methylation and the stable warfarin dose through genome-wide DNA methylation analysis and pyrosequencing assay. METHOD: This study included 161 patients and genome-wide DNA methylation analysis was used to screen potential warfarin dose-associate...

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Detalles Bibliográficos
Autores principales:	He, Shiwei, Wu, Yuan, Yan, Shuidi, Liu, Jumei, Zhao, Li, Xie, Huabin, Ge, Shengxiang, Ye, Huiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2021
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231338/ https://www.ncbi.nlm.nih.gov/pubmed/34221714 http://dx.doi.org/10.7717/peerj.11549

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