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Synthesis, biological evaluation and molecular docking investigation of new sulphonamide derivatives bearing naphthalene moiety as potent tubulin polymerisation inhibitors

A new series of sulphonamide derivatives bearing naphthalene moiety were synthesised and evaluated for their antiproliferative and tubulin polymerisation inhibitory activities. These new compounds were evaluated for their in vitro antiproliferative activity against MCF-7 and A549 by using CCK-8 meth...

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Detalles Bibliográficos
Autores principales: Wang, Guangcheng, Fan, Meiyan, Liu, Wenjing, He, Min, Li, Yongjun, Peng, Zhiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231400/
https://www.ncbi.nlm.nih.gov/pubmed/34157927
http://dx.doi.org/10.1080/14756366.2021.1943378