ATF4-dependent heme-oxygenase-1 attenuates diabetic nephropathy by inducing autophagy and inhibiting apoptosis in podocyte

AIM: Podocyte injury plays an important role in diabetic nephropathy (DN), yet the underlying molecular mechanisms of podocyte injury in DN is not clear. Here, we investigated the role of activating transcription factor 4 (ATF4) and HO-1 in DN-induced podocyte injury. METHODS: Protein expression was...

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Detalles Bibliográficos
Autores principales: Yuan, Shizhu, Liang, Xudong, He, Wenfang, Liang, Mingzhu, Jin, Juan, He, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231401/
https://www.ncbi.nlm.nih.gov/pubmed/34157937
http://dx.doi.org/10.1080/0886022X.2021.1936040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231401/
https://www.ncbi.nlm.nih.gov/pubmed/34157937
http://dx.doi.org/10.1080/0886022X.2021.1936040

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