A Deep-Learning Sequence-Based Method to Predict Protein Stability Changes Upon Genetic Variations

Several studies have linked disruptions of protein stability and its normal functions to disease. Therefore, during the last few decades, many tools have been developed to predict the free energy changes upon protein residue variations. Most of these methods require both sequence and structure infor...

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Detalles Bibliográficos
Autores principales: Pancotti, Corrado, Benevenuta, Silvia, Repetto, Valeria, Birolo, Giovanni, Capriotti, Emidio, Sanavia, Tiziana, Fariselli, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231498/
https://www.ncbi.nlm.nih.gov/pubmed/34204764
http://dx.doi.org/10.3390/genes12060911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231498/
https://www.ncbi.nlm.nih.gov/pubmed/34204764
http://dx.doi.org/10.3390/genes12060911

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