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A Deep-Learning Sequence-Based Method to Predict Protein Stability Changes Upon Genetic Variations
Several studies have linked disruptions of protein stability and its normal functions to disease. Therefore, during the last few decades, many tools have been developed to predict the free energy changes upon protein residue variations. Most of these methods require both sequence and structure infor...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231498/ https://www.ncbi.nlm.nih.gov/pubmed/34204764 http://dx.doi.org/10.3390/genes12060911 |