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A Biophysical Insight of Camptothecin Biodistribution: Towards a Molecular Understanding of Its Pharmacokinetic Issues

Camptothecin (CPT) is a potent anticancer drug, and its putative oral administration is envisioned although difficult due to physiological barriers that must be overcome. A comprehensive biophysical analysis of CPT interaction with biointerface models can be used to predict some pharmacokinetic issu...

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Detalles Bibliográficos
Autores principales: Almeida, Andreia, Fernandes, Eduarda, Sarmento, Bruno, Lúcio, Marlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231504/
https://www.ncbi.nlm.nih.gov/pubmed/34204692
http://dx.doi.org/10.3390/pharmaceutics13060869