New Heparanase-Inhibiting Triazolo-Thiadiazoles Attenuate Primary Tumor Growth and Metastasis

SIMPLE SUMMARY: Heparanase is an endoglycosidase that plays a critical role in tumor progression and metastasis. The expression of heparanase in the tumor microenvironment is positively correlated with the aggressiveness of the tumor and is associated with poor prognosis. In this study, we have demo...

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Detalles Bibliográficos
Autores principales: Barash, Uri, Rangappa, Shobith, Mohan, Chakrabhavi Dhananjaya, Vishwanath, Divakar, Boyango, Ilanit, Basappa, Basappa, Vlodavsky, Israel, Rangappa, Kanchugarakoppal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231572/
https://www.ncbi.nlm.nih.gov/pubmed/34199150
http://dx.doi.org/10.3390/cancers13122959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231572/
https://www.ncbi.nlm.nih.gov/pubmed/34199150
http://dx.doi.org/10.3390/cancers13122959

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