Molecular Dynamics Simulations of a Cytochrome P450 from Tepidiphilus thermophilus (P450-TT) Reveal How Its Substrate-Binding Channel Opens

Cytochrome P450s (P450) are important enzymes in biology with useful biochemical reactions in, for instance, drug and xenobiotics metabolisms, biotechnology, and health. Recently, the crystal structure of a new member of the CYP116B family has been resolved. This enzyme is a cytochrome P450 (CYP116B...

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Detalles Bibliográficos
Autores principales: Faponle, Abayomi S., Roy, Anupom, Adelegan, Ayodeji A., Gauld, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231624/
https://www.ncbi.nlm.nih.gov/pubmed/34204747
http://dx.doi.org/10.3390/molecules26123614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231624/
https://www.ncbi.nlm.nih.gov/pubmed/34204747
http://dx.doi.org/10.3390/molecules26123614

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