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Facile Synthesis of 2H-Benzo[h]Chromenes via an Arylamine-Catalyzed Mannich Cyclization Cascade Reaction

A simple arylamine-catalyzed Mannich-cyclization cascade reaction was developed for facile synthesis of substituted 2H-benzo[h]chromenes. The notable feature of the process included the efficient generation of ortho-quinone methides (o-QMs) catalyzed by a simple aniline. The mild reaction conditions...

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Detalles Bibliográficos
Autores principales: Zhang, Yueteng, Ji, Peng, Meng, Xiang, Gao, Feng, Zeng, Fanxun, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231631/
https://www.ncbi.nlm.nih.gov/pubmed/34204782
http://dx.doi.org/10.3390/molecules26123617