Multiple Roles of SARS-CoV-2 N Protein Facilitated by Proteoform-Specific Interactions with RNA, Host Proteins, and Convalescent Antibodies

[Image: see text] The SARS-CoV-2 nucleocapsid (N) protein is a highly immunogenic viral protein that plays essential roles in replication and virion assembly. Here, using native mass spectrometry, we show that dimers are the functional unit of ribonucleoprotein assembly and that N protein binds RNA...

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Detalles Bibliográficos
Autores principales: Lutomski, Corinne A., El-Baba, Tarick J., Bolla, Jani R., Robinson, Carol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231660/
https://www.ncbi.nlm.nih.gov/pubmed/34462738
http://dx.doi.org/10.1021/jacsau.1c00139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231660/
https://www.ncbi.nlm.nih.gov/pubmed/34462738
http://dx.doi.org/10.1021/jacsau.1c00139

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