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Paracrine Signaling from a Three-Dimensional Model of Bladder Carcinoma and from Normal Bladder Switch the Phenotype of Stromal Fibroblasts

SIMPLE SUMMARY: The aim of this work was to create a bladder carcinoma model to study the signals secreted by carcinoma cells in a in vivo-like context and how this molecular signaling can alter stromal fibroblasts. Our model is based on decellularized organ fragments (scaffolds) that aim to preserv...

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Detalles Bibliográficos
Autores principales: Camargo, Sandra, Gofrit, Ofer N., Assis, Assaf, Mitrani, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231763/
https://www.ncbi.nlm.nih.gov/pubmed/34198488
http://dx.doi.org/10.3390/cancers13122972