Gap Junction-Mediated Intercellular Communication of cAMP Prevents CDDP-Induced Ototoxicity via cAMP/PKA/CREB Pathway

In the cochlea, non-sensory supporting cells are directly connected to adjacent supporting cells via gap junctions that allow the exchange of small molecules. We have previously shown that the pharmacological regulation of gap junctions alleviates cisplatin (CDDP)-induced ototoxicity in animal model...

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Detalles Bibliográficos
Autores principales: Kim, Yeon Ju, Lee, Jin-Sol, Kim, Hantai, Jang, Jeong Hun, Choung, Yun-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231879/
https://www.ncbi.nlm.nih.gov/pubmed/34199197
http://dx.doi.org/10.3390/ijms22126327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231879/
https://www.ncbi.nlm.nih.gov/pubmed/34199197
http://dx.doi.org/10.3390/ijms22126327

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