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Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of ob/ob Mice

The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the eye (ACE), pancreatic islets engraft and maintain morphological features of native islets as we...

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Detalles Bibliográficos
Autores principales: Leibiger, Barbara, Moede, Tilo, Valladolid-Acebes, Ismael, Paschen, Meike, Visa, Montse, Leibiger, Ingo B., Berggren, Per-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231910/
https://www.ncbi.nlm.nih.gov/pubmed/34198579
http://dx.doi.org/10.3390/metabo11060387