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Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of ob/ob Mice
The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the eye (ACE), pancreatic islets engraft and maintain morphological features of native islets as we...
Autores principales: | Leibiger, Barbara, Moede, Tilo, Valladolid-Acebes, Ismael, Paschen, Meike, Visa, Montse, Leibiger, Ingo B., Berggren, Per-Olof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231910/ https://www.ncbi.nlm.nih.gov/pubmed/34198579 http://dx.doi.org/10.3390/metabo11060387 |
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