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Characterization of Two NMN Deamidase Mutants as Possible Probes for an NMN Biosensor

Nicotinamide mononucleotide (NMN) is a key intermediate in the nicotinamide adenine dinucleotide (NAD+) biosynthesis. Its supplementation has demonstrated beneficial effects on several diseases. The aim of this study was to characterize NMN deamidase (PncC) inactive mutants to use as possible molecu...

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Detalles Bibliográficos
Autores principales: Camarca, Alessandra, Minazzato, Gabriele, Pennacchio, Angela, Capo, Alessandro, Amici, Adolfo, D’Auria, Sabato, Raffaelli, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8231969/
https://www.ncbi.nlm.nih.gov/pubmed/34199271
http://dx.doi.org/10.3390/ijms22126334