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The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction

Exposure to hydrochloric acid (HCl) leads acutely to asthma-like symptoms, acute respiratory distress syndrome (ARDS), including compromised alveolo-capillary barrier, and respiratory failure. To better understand the direct effects of HCl on pulmonary endothelial function, we studied the characteri...

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Detalles Bibliográficos
Autores principales: Colunga Biancatelli, Ruben M. L., Solopov, Pavel, Gregory, Betsy, Catravas, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232030/
https://www.ncbi.nlm.nih.gov/pubmed/34199261
http://dx.doi.org/10.3390/cells10061489