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Carbamazepine Reduces Sharp Wave-Ripple Complexes and Exerts Synapse-Specific Inhibition of Neurotransmission in Ex Vivo Hippocampal Slices

Higher therapeutic concentrations of the antiseizure medication carbamazepine (CBZ) are associated with cognitive side effects. Hippocampal sharp wave-ripple complexes (SPW-Rs) are proposed to participate in memory consolidation during periods of quiet and slow-wave sleep. SPW-Rs are generated in th...

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Detalles Bibliográficos
Autores principales: Simeone, Timothy A., Heruye, Segewkal H., Kostansek, Joseph A., Yeh, Mary Y., Matthews, Stephanie A., Samson, Kaeli K., Simeone, Kristina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232098/
https://www.ncbi.nlm.nih.gov/pubmed/34203601
http://dx.doi.org/10.3390/brainsci11060787