Multi-Target Directed Ligands (MTDLs) Binding the σ(1) Receptor as Promising Therapeutics: State of the Art and Perspectives

The sigma-1 (σ(1)) receptor is a ‘pluripotent chaperone’ protein mainly expressed at the mitochondria–endoplasmic reticulum membrane interfaces where it interacts with several client proteins. This feature renders the σ(1) receptor an ideal target for the development of multifunctional ligands, whos...

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Detalles Bibliográficos
Autores principales: Abatematteo, Francesca Serena, Niso, Mauro, Contino, Marialessandra, Leopoldo, Marcello, Abate, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232171/
https://www.ncbi.nlm.nih.gov/pubmed/34198620
http://dx.doi.org/10.3390/ijms22126359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232171/
https://www.ncbi.nlm.nih.gov/pubmed/34198620
http://dx.doi.org/10.3390/ijms22126359

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