(-)-Englerin-A Has Analgesic and Anti-Inflammatory Effects Independent of TRPC4 and 5

Recently, we found that the deletion of TRPC5 leads to increased inflammation and pain-related behaviour in two animal models of arthritis. (-)-Englerin A (EA), an extract from the East African plant Phyllanthus engleri has been identified as a TRPC4/5 agonist. Here, we studied whether or not EA has...

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Detalles Bibliográficos
Autores principales: de Sousa Valente, João, Alawi, Khadija M, Bharde, Sabah, Zarban, Ali A., Kodji, Xenia, Thapa, Dibesh, Argunhan, Fulye, Barrett, Brentton, Nagy, Istvan, Brain, Susan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232259/
https://www.ncbi.nlm.nih.gov/pubmed/34203675
http://dx.doi.org/10.3390/ijms22126380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232259/
https://www.ncbi.nlm.nih.gov/pubmed/34203675
http://dx.doi.org/10.3390/ijms22126380

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