Rapid Conversion of Amyloid-Beta 1-40 Oligomers to Mature Fibrils through a Self-Catalytic Bimolecular Process

The formation of fibrillar aggregates of the amyloid beta peptide (Aβ) in the brain is one of the hallmarks of Alzheimer’s disease (AD). A clear understanding of the different aggregation steps leading to fibrils formation is a keystone in therapeutics discovery. In a recent study, we showed that Aβ...

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Detalles Bibliográficos
Autores principales: Morel, Bertrand, Carrasco-Jiménez, María P., Jurado, Samuel, Conejero-Lara, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232289/
https://www.ncbi.nlm.nih.gov/pubmed/34198692
http://dx.doi.org/10.3390/ijms22126370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232289/
https://www.ncbi.nlm.nih.gov/pubmed/34198692
http://dx.doi.org/10.3390/ijms22126370

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