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Rapid Conversion of Amyloid-Beta 1-40 Oligomers to Mature Fibrils through a Self-Catalytic Bimolecular Process
The formation of fibrillar aggregates of the amyloid beta peptide (Aβ) in the brain is one of the hallmarks of Alzheimer’s disease (AD). A clear understanding of the different aggregation steps leading to fibrils formation is a keystone in therapeutics discovery. In a recent study, we showed that Aβ...
Autores principales: | Morel, Bertrand, Carrasco-Jiménez, María P., Jurado, Samuel, Conejero-Lara, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232289/ https://www.ncbi.nlm.nih.gov/pubmed/34198692 http://dx.doi.org/10.3390/ijms22126370 |
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