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Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP

The toolbox for genetic engineering has quickly evolved from CRISPR/Cas9 to a myriad of different gene editors, each with promising properties and enormous clinical potential. However, a major challenge remains: delivering the CRISPR machinery to the nucleus of recipient cells in a nontoxic and effi...

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Detalles Bibliográficos
Autores principales: Gustafsson, Oskar, Rädler, Julia, Roudi, Samantha, Lehto, Tõnis, Hällbrink, Mattias, Lehto, Taavi, Gupta, Dhanu, Andaloussi, Samir EL, Nordin, Joel Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232299/
https://www.ncbi.nlm.nih.gov/pubmed/34198625
http://dx.doi.org/10.3390/pharmaceutics13060878