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Design, development and optimization of sustained release floating, bioadhesive and swellable matrix tablet of ranitidine hydrochloride

Ranitidine HCl, a selective, competitive histamine H(2)-receptor antagonist with a short biological half-life, low bioavailability and narrow absorption window, is an ideal candidate for gastro-retentive drug delivery system (GRDDS). Controlled release with an optimum retentive formulation in the up...

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Detalles Bibliográficos
Autores principales: Nigusse, Birhanu, Gebre-Mariam, Tsige, Belete, Anteneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232414/
https://www.ncbi.nlm.nih.gov/pubmed/34170952
http://dx.doi.org/10.1371/journal.pone.0253391