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The effect of human amnion epithelial cells on lung development and inflammation in preterm lambs exposed to antenatal inflammation

BACKGROUND: Lung inflammation and impaired alveolarization are hallmarks of bronchopulmonary dysplasia (BPD). We hypothesize that human amnion epithelial cells (hAECs) are anti-inflammatory and reduce lung injury in preterm lambs born after antenatal exposure to inflammation. METHODS: Pregnant ewes...

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Detalles Bibliográficos
Autores principales: Papagianis, Paris Clarice, Ahmadi-Noorbakhsh, Siavash, Lim, Rebecca, Wallace, Euan, Polglase, Graeme, Pillow, J. Jane, Moss, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232434/
https://www.ncbi.nlm.nih.gov/pubmed/34170941
http://dx.doi.org/10.1371/journal.pone.0253456