In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides

Cancer and other disease states can change the landscape of proteins post-translationally tagged with ubiquitin (Ub) chains. Molecules capable of modulating the functions of Ub chains are potential therapeutic agents, but their discovery represents a significant challenge. Recently, it was shown tha...

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Detalles Bibliográficos
Autores principales: Rogers, Joseph M., Nawatha, Mickal, Lemma, Betsegaw, Vamisetti, Ganga B., Livneh, Ido, Barash, Uri, Vlodavsky, Israel, Ciechanover, Aaron, Fushman, David, Suga, Hiroaki, Brik, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232551/
https://www.ncbi.nlm.nih.gov/pubmed/34179781
http://dx.doi.org/10.1039/d0cb00179a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8232551/
https://www.ncbi.nlm.nih.gov/pubmed/34179781
http://dx.doi.org/10.1039/d0cb00179a

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